Zhong-Yin Zhang Selected Research

ras Proteins

1/2019

Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation.

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Zhong-Yin Zhang Research Topics

Disease

53	Neoplasms (Cancer) 04/2024 - 04/2004
15	Obesity 11/2022 - 02/2003
11	Neoplasm Metastasis (Metastasis) 04/2024 - 01/2006
8	Autoimmune Diseases (Autoimmune Disease) 07/2021 - 12/2007
8	Carcinogenesis 01/2020 - 02/2007
6	Leukemia 09/2023 - 01/2011
5	Breast Neoplasms (Breast Cancer) 01/2023 - 06/2006
5	Type 2 Diabetes Mellitus (MODY) 10/2015 - 02/2003
5	Plague (Bubonic Plague) 08/2010 - 08/2003
4	Infections 01/2022 - 11/2013
4	Tuberculosis (Tuberculoses) 03/2016 - 03/2013
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2023 - 10/2014
3	Ovarian Neoplasms (Ovarian Cancer) 01/2019 - 07/2011
3	Fibrosis (Cirrhosis) 01/2018 - 08/2014
3	Rheumatoid Arthritis 05/2016 - 12/2007
3	Noonan Syndrome (Female Pseudo-Turner Syndrome) 01/2016 - 01/2011
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2015 - 02/2010
2	Hematologic Neoplasms (Hematological Malignancy) 04/2024 - 01/2014
2	Colorectal Neoplasms (Colorectal Cancer) 01/2023 - 06/2017
2	Inflammation (Inflammations) 01/2018 - 01/2017
2	Communicable Diseases (Infectious Diseases) 01/2017 - 03/2012
2	Neuroinflammatory Diseases 10/2016 - 04/2016
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2016 - 12/2007
2	Insulin Resistance 10/2015 - 10/2012
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/2005 - 11/2003
1	Experimental Melanoma 11/2023
1	Acute Kidney Injury (Acute Renal Failure) 01/2023
1	Adenocarcinoma 01/2023
1	Alzheimer Disease (Alzheimer's Disease) 01/2023
1	Bites and Stings (Sting) 01/2023
1	Cough 01/2023
1	Hypertension (High Blood Pressure) 01/2023
1	Status Epilepticus (Complex Partial Status Epilepticus) 05/2022
1	Glioblastoma (Glioblastoma Multiforme) 01/2022
1	Seizures (Absence Seizure) 01/2022
1	Brain Neoplasms (Brain Tumor) 01/2022

Drug/Important Bio-Agent (IBA)

40	Phosphoric Monoester Hydrolases (Phosphatases)IBA 04/2024 - 02/2003
24	Protein Tyrosine PhosphatasesIBA 04/2024 - 08/2003
17	Tyrosine (L-Tyrosine)FDA Link 10/2023 - 05/2007
10	Non-Receptor Type 1 Protein Tyrosine PhosphataseIBA 01/2023 - 11/2003
8	Proteins (Proteins, Gene)FDA Link 04/2024 - 03/2012
8	6-pyruvoyltetrahydropterin synthase (PTPS)IBA 12/2023 - 06/2008
7	LeptinIBA 11/2022 - 02/2003
7	Insulin (Novolin)FDA Link 01/2018 - 02/2003
5	Non-Receptor Type 2 Protein Tyrosine PhosphataseIBA 11/2023 - 01/2013
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 10/2022 - 06/2008
4	Oncogene Proteins (Oncogene Protein)IBA 02/2018 - 07/2011
4	Virulence Factors (Pathogenicity Factors)IBA 03/2016 - 08/2003
3	PTEN Phosphohydrolase (PTEN Phosphatase)IBA 10/2023 - 07/2008
3	Paclitaxel (Taxol)FDA LinkGeneric 01/2019 - 07/2011
3	Non-Receptor Type 11 Protein Tyrosine PhosphataseIBA 01/2018 - 05/2016
3	Glucose (Dextrose)FDA LinkGeneric 01/2015 - 10/2012
3	Phosphotransferases (Kinase)IBA 03/2014 - 06/2006
3	ErbB Receptors (EGF Receptor)IBA 10/2013 - 01/2006
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 11/2023 - 07/2021
2	InterferonsIBA 01/2023 - 01/2017
2	Phospholipases A2 (Phospholipase A2)IBA 01/2023 - 07/2011
2	Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)IBA 01/2023 - 06/2017
2	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 10/2022 - 01/2014
2	Insulin ReceptorIBA 01/2018 - 11/2003
2	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 01/2018 - 01/2015
2	Small Interfering RNA (siRNA)IBA 06/2017 - 11/2013
2	CytokinesIBA 01/2016 - 01/2015
2	Biomarkers (Surrogate Marker)IBA 01/2014 - 02/2010
1	Therapeutic UsesIBA 04/2024
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 09/2023
1	AntigensIBA 06/2023
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2023
1	coomassie Brilliant BlueIBA 01/2023
1	leucylleucine (Leu-Leu)IBA 01/2023
1	cloperastineIBA 01/2023
1	candesartan cilexetil (Amias)FDA Link 01/2023
1	4-O-(sulfamoyl)-N-tetradecanoyltyramine (DU 14)IBA 01/2023
1	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2023
1	Deubiquitinating EnzymesIBA 01/2023
1	ATPases Associated with Diverse Cellular ActivitiesIBA 01/2023
1	Valosin Containing ProteinIBA 01/2023
1	Lysosomal-Associated Membrane Protein 1IBA 01/2023
1	Green Fluorescent ProteinsIBA 01/2023
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2023
1	Galectin 3 (LGALS3)IBA 01/2023
1	EstersIBA 01/2023
1	UbiquitinIBA 01/2023
1	Glycerol (Glycerine)FDA LinkGeneric 01/2023
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2023
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2023
1	TransferasesIBA 01/2023
1	Transcription Factors (Transcription Factor)IBA 01/2023
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 10/2022
1	Anticonvulsants (Antiepileptic Drugs)IBA 05/2022
1	ArrestinIBA 01/2022
1	PQR530IBA 01/2022
1	AmylopectinIBA 01/2022
1	Immune Checkpoint InhibitorsIBA 01/2022
1	beta-Arrestin 1IBA 01/2022
1	Polysaccharides (Glycans)IBA 01/2022
1	RE1-silencing transcription factorIBA 01/2022
1	4- (alpha- (4- allyl- 2,5- dimethyl- 1- piperazinyl)- 3- methoxybenzyl)- N,N- diethylbenzamideIBA 01/2022

Therapy/Procedure

23	Therapeutics 04/2024 - 02/2003
5	Immunotherapy 12/2023 - 07/2021